| Standings | P | W | D | L | GD | PTS | |
|---|---|---|---|---|---|---|---|
| 1 | Philadelphia Union | 12 | 8 | 3 | 1 | 13 | 27 |
| 2 | FC Cincinnati | 11 | 7 | 2 | 2 | 7 | 23 |
| 3 | Nashville SC | 12 | 8 | 3 | 1 | 16 | 27 |
| 4 | San Diego FC | 12 | 6 | 3 | 3 | 10 | 21 |
| 5 | Vancouver Whitecaps | 10 | 6 | 2 | 2 | 9 | 20 |
| 6 | Columbus Crew | 12 | 7 | 4 | 1 | 9 | 25 |
| 7 | Minnesota United | 12 | 6 | 3 | 3 | 9 | 21 |
| 8 | Inter Miami CF | 10 | 6 | 2 | 2 | 8 | 20 |
| 9 | Los Angeles FC | 11 | 8 | 1 | 2 | 14 | 25 |
| 10 | Orlando City SC | 12 | 5 | 3 | 4 | 5 | 18 |
| 11 | New York City FC | 11 | 8 | 0 | 3 | 9 | 24 |
| 12 | Seattle Sounders | 11 | 6 | 4 | 1 | 12 | 22 |
| 13 | New York Red Bulls | 11 | 8 | 2 | 1 | 17 | 26 |
| 14 | Portland Timbers | 12 | 6 | 4 | 2 | 3 | 22 |
| 15 | Charlotte FC | 11 | 8 | 1 | 2 | 11 | 25 |
| 16 | Colorado Rapids | 13 | 6 | 2 | 5 | 1 | 20 |
| 17 | Austin FC | 11 | 4 | 5 | 2 | 0 | 17 |
| 18 | Chicago Fire | 10 | 2 | 4 | 4 | -3 | 10 |
| 19 | San Jose Earthquakes | 12 | 3 | 6 | 3 | 8 | 15 |
| 20 | Real Salt Lake | 10 | 5 | 1 | 4 | 3 | 16 |
| 21 | Houston Dynamo | 12 | 4 | 1 | 7 | -8 | 13 |
| 22 | New England Revolution | 9 | 2 | 2 | 5 | -3 | 8 |
| 23 | Sporting Kansas City | 11 | 3 | 3 | 5 | -4 | 12 |
| 24 | FC Dallas | 10 | 1 | 2 | 7 | -9 | 5 |
| 25 | Toronto FC | 13 | 2 | 4 | 7 | -4 | 10 |
| 26 | Atlanta United | 11 | 4 | 4 | 3 | 2 | 16 |
| 27 | DC United | 12 | 2 | 5 | 5 | -9 | 11 |
| 28 | St. Louis City SC | 11 | 3 | 4 | 4 | -2 | 13 |
| 29 | Los Angeles Galaxy | 11 | 3 | 2 | 6 | -4 | 11 |
| 30 | CF Montreal | 10 | 1 | 3 | 6 | -14 | 6 |
