| Standings | P | W | D | L | GD | PTS | |
|---|---|---|---|---|---|---|---|
| 1 | Philadelphia Union | 11 | 6 | 1 | 4 | 4 | 19 |
| 2 | FC Cincinnati | 12 | 7 | 1 | 4 | 0 | 22 |
| 3 | Nashville SC | 11 | 5 | 2 | 4 | 0 | 17 |
| 4 | San Diego FC | 11 | 7 | 0 | 4 | 5 | 21 |
| 5 | Vancouver Whitecaps | 12 | 6 | 3 | 3 | 4 | 21 |
| 6 | Columbus Crew | 11 | 4 | 4 | 3 | -3 | 16 |
| 7 | Minnesota United | 11 | 5 | 4 | 2 | 4 | 19 |
| 8 | Inter Miami CF | 10 | 5 | 3 | 2 | 3 | 18 |
| 9 | Los Angeles FC | 9 | 2 | 4 | 3 | -2 | 10 |
| 10 | Orlando City SC | 11 | 4 | 5 | 2 | 5 | 17 |
| 11 | New York City FC | 11 | 2 | 4 | 5 | -5 | 10 |
| 12 | Seattle Sounders | 11 | 3 | 3 | 5 | -9 | 12 |
| 13 | New York Red Bulls | 12 | 1 | 4 | 7 | -9 | 7 |
| 14 | Portland Timbers | 10 | 3 | 2 | 5 | -3 | 11 |
| 15 | Charlotte FC | 12 | 2 | 1 | 9 | -10 | 7 |
| 16 | Colorado Rapids | 11 | 2 | 4 | 5 | -7 | 10 |
| 17 | Austin FC | 11 | 4 | 1 | 6 | -7 | 13 |
| 18 | Chicago Fire | 12 | 6 | 1 | 5 | 5 | 19 |
| 19 | San Jose Earthquakes | 11 | 4 | 2 | 5 | -3 | 14 |
| 20 | Real Salt Lake | 12 | 3 | 3 | 6 | -7 | 12 |
| 21 | Houston Dynamo | 11 | 3 | 4 | 4 | -1 | 13 |
| 22 | New England Revolution | 13 | 4 | 5 | 4 | 2 | 17 |
| 23 | Sporting Kansas City | 11 | 3 | 2 | 6 | -2 | 11 |
| 24 | FC Dallas | 12 | 4 | 5 | 3 | -3 | 17 |
| 25 | Toronto FC | 9 | 3 | 2 | 4 | 0 | 11 |
| 26 | Atlanta United | 11 | 0 | 4 | 7 | -17 | 4 |
| 27 | DC United | 11 | 2 | 2 | 7 | -15 | 8 |
| 28 | St. Louis City SC | 11 | 1 | 2 | 8 | -10 | 5 |
| 29 | Los Angeles Galaxy | 12 | 0 | 4 | 8 | -16 | 4 |
| 30 | CF Montreal | 13 | 2 | 3 | 8 | -9 | 9 |
