| Standings | P | W | D | L | GD | PTS | |
|---|---|---|---|---|---|---|---|
| 1 | Louisville City | 10 | 8 | 2 | 0 | 16 | 26 |
| 2 | Charleston Battery | 9 | 8 | 0 | 1 | 16 | 24 |
| 3 | Tulsa Roughnecks | 10 | 6 | 2 | 2 | 6 | 20 |
| 4 | Loudoun United | 10 | 6 | 2 | 2 | 6 | 20 |
| 5 | Sacramento Republic | 11 | 4 | 6 | 1 | 9 | 18 |
| 6 | North Carolina | 10 | 6 | 2 | 2 | 6 | 20 |
| 7 | El Paso Locomotive | 9 | 4 | 3 | 2 | 8 | 15 |
| 8 | San Antonio | 11 | 5 | 1 | 5 | 2 | 16 |
| 9 | Orange County SC | 9 | 6 | 1 | 2 | 7 | 19 |
| 10 | Pittsburgh Riverhounds | 11 | 6 | 3 | 2 | 6 | 21 |
| 11 | New Mexico United | 8 | 4 | 2 | 2 | 3 | 14 |
| 12 | Detroit City | 8 | 3 | 3 | 2 | 2 | 12 |
| 13 | Lexington SC | 10 | 4 | 4 | 2 | 3 | 16 |
| 14 | Phoenix Rising | 8 | 2 | 3 | 3 | 1 | 9 |
| 15 | Colorado Springs | 8 | 3 | 2 | 3 | 1 | 11 |
| 16 | Hartford Athletic | 11 | 4 | 3 | 4 | 6 | 15 |
| 17 | Monterey Bay FC | 9 | 5 | 1 | 3 | 2 | 16 |
| 18 | Oakland Roots SC | 10 | 2 | 2 | 6 | -6 | 8 |
| 19 | Rhode Island FC | 10 | 2 | 5 | 3 | -2 | 11 |
| 20 | Indy Eleven | 10 | 3 | 3 | 4 | -1 | 12 |
| 21 | Las Vegas Lights | 11 | 4 | 2 | 5 | -3 | 14 |
| 22 | Miami FC | 12 | 3 | 3 | 6 | -6 | 12 |
| 23 | Birmingham Legion | 11 | 2 | 3 | 6 | -6 | 9 |
| 24 | Tampa Bay Rowdies | 8 | 2 | 2 | 4 | -4 | 8 |