| Standings | P | W | D | L | GD | PTS | |
|---|---|---|---|---|---|---|---|
| 1 | Philadelphia Union | 12 | 6 | 2 | 4 | 4 | 20 |
| 2 | San Diego FC | 12 | 8 | 0 | 4 | 7 | 24 |
| 3 | FC Cincinnati | 14 | 8 | 2 | 4 | 1 | 26 |
| 4 | Nashville SC | 13 | 5 | 2 | 6 | -3 | 17 |
| 5 | Vancouver Whitecaps | 14 | 6 | 4 | 4 | 3 | 22 |
| 6 | Orlando City SC | 13 | 6 | 5 | 2 | 8 | 23 |
| 7 | Minnesota United | 13 | 6 | 5 | 2 | 5 | 23 |
| 8 | Columbus Crew | 11 | 4 | 4 | 3 | -3 | 16 |
| 9 | Inter Miami CF | 12 | 6 | 3 | 3 | 4 | 21 |
| 10 | Charlotte FC | 14 | 4 | 1 | 9 | -8 | 13 |
| 11 | Seattle Sounders | 13 | 4 | 4 | 5 | -5 | 16 |
| 12 | New York City FC | 13 | 3 | 5 | 5 | -4 | 14 |
| 13 | Los Angeles FC | 10 | 2 | 5 | 3 | -2 | 11 |
| 14 | Portland Timbers | 12 | 4 | 2 | 6 | -4 | 14 |
| 15 | Chicago Fire | 13 | 7 | 1 | 5 | 7 | 22 |
| 16 | New York Red Bulls | 13 | 1 | 4 | 8 | -10 | 7 |
| 17 | Austin FC | 12 | 5 | 1 | 6 | -5 | 16 |
| 18 | Colorado Rapids | 13 | 3 | 4 | 6 | -8 | 13 |
| 19 | San Jose Earthquakes | 13 | 4 | 2 | 7 | -5 | 14 |
| 20 | Real Salt Lake | 13 | 3 | 3 | 7 | -8 | 12 |
| 21 | New England Revolution | 13 | 4 | 5 | 4 | 2 | 17 |
| 22 | FC Dallas | 12 | 4 | 5 | 3 | -3 | 17 |
| 23 | Houston Dynamo | 12 | 3 | 5 | 4 | -1 | 14 |
| 24 | Sporting Kansas City | 12 | 3 | 2 | 7 | -5 | 11 |
| 25 | Toronto FC | 12 | 3 | 3 | 6 | -3 | 12 |
| 26 | Atlanta United | 12 | 0 | 5 | 7 | -17 | 5 |
| 27 | St. Louis City SC | 12 | 1 | 2 | 9 | -13 | 5 |
| 28 | CF Montreal | 14 | 3 | 3 | 8 | -7 | 12 |
| 29 | DC United | 13 | 2 | 2 | 9 | -18 | 8 |
| 30 | Los Angeles Galaxy | 13 | 0 | 5 | 8 | -16 | 5 |
